关键词: SPF 级, 比格犬, 不同月龄, 血液生化指标

Abstract: Objective To study and explore the changes of blood biochemical indexes in SPF dogs at different months of age. Method The experiment randomly selected healthy Beagles of different months of age, 12 Beagles of 2, 6 and 9 months of age, and collected 10 mL blood from forelimb vein. The blood biochemical indexes were detected. Result The content of inorganic salts in the blood of SPF Beagles was rich, and the content of Na ions was the most, and the fluctuation was not obvious. Serum alanine aminotransferase (ALT) fluctuated greatly from 2,6, 9 months of age, but there was no significant difference. Total bilirubin ( TBIL) content did not change significantly during the growth of SPF dogs, but remained stable. Although the content of blood glucose and blood lipid fluctuated little during the growth process, it was relatively stable. Conclusion The blood biochemical indices of SPF class Beagles at different months of age fluctuated, and the result of this study will provide basic information for the subsequent breeding and experimental design of SPF class Beagles.

Key words: SPF, Beagle, different months, blood biochemical index